The Science of Longevity: Beyond Numbers

Longevity, in simple terms, is the span of an individual's life, shaped by genetics, lifestyle choices, and environmental factors. Central to the ageing process are molecular mechanisms influenced by these factors, leading to what can be described as 'ageing as a disease'. This concept, supported by the 2023 hallmarks of ageing paper, identifies key ageing drivers as the root causes of age-related diseases. These molecular drivers and mechanisms such as DNA repair, mitochondrial dysfunction, gut microbiome dysbiosis etc. are essentially the underlying causes of many age-related diseases, positioning ageing as the primary risk factor for these conditions.

Traditionally, healthcare has adopted a "one disease, one treatment" approach, addressing age-related diseases individually. In contrast, the emerging "longevity thinking" paradigm advocates for targeting ageing's underlying mechanisms to simultaneously combat multiple age-related conditions.

This strategy aims not just to extend life but to enhance its quality by focusing on preventive care and holistic well-being. By addressing the root causes of ageing, longevity thinking seeks to improve overall health and extend a healthy lifespan, rather than simply treating individual diseases as they arise.

This paradigm shift represents a more holistic and efficient approach to healthcare, emphasizing prevention and the maintenance of overall well-being as we age. Highlighting longevity thinking's innovative approach, such as its potential to prevent diseases by addressing ageing's root causes, can make the benefits more tangible.

Redefining the Wellness Industry: Building Longevity Ecosystem

By introducing the "longevity ecosystem," we see a strategy in India focused on enhancing life for the elderly. This approach isn't just about extending lives but enriching them too. It represents a shift towards

preventive healthcare, emphasizing keeping people healthy before illness strikes and prioritizing the dignity and well-being of the elderly.

From a financial and biomedical perspective, building this ecosystem is crucial as India's population ages. It involves collaboration, innovation, and a commitment to creating an environment that supports ageing well. Developing a longevity ecosystem in India is an ongoing effort that will evolve with continuous research and collaboration.

As a driving force behind India's longevity ecosystem, Decode Age contributes significantly through research, innovation, and advocacy. The initiative aims to transform ageing into a positive phase of life marked by health and happiness. Looking forward, this ecosystem offers hope and points India towards a future where its ageing population thrives, potentially easing the financial strain on healthcare systems and boosting the economy.

— Parth Amin

(The author is CEO & Co-Founder, Decode Age)

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